T‐bet + memory B cells: Generation, function, and fate
نویسندگان
چکیده
منابع مشابه
IFNγ inhibits Th17 differentiation and function via Tbet-dependent and Tbet-independent mechanisms
The transcription factor Tbet is critical for the differentiation of Th1 CD4 T cells and is associated with the induction of multiple autoimmune diseases, including experimental autoimmune encephalomyelitis (EAE). Herein, we demonstrate that Tbet suppresses IL-17A and Th17 differentiation both in vitro and in vivo in a cell-intrinsic manner, and that in fact, Tbet is not necessary for EAE induc...
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ژورنال
عنوان ژورنال: Immunological Reviews
سال: 2019
ISSN: 0105-2896,1600-065X
DOI: 10.1111/imr.12736